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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

Catecholamine determinations showed that the administration of doxorubicin under hyperthermic conditions increased the liberation of both epinephrine and norepinephrine.
JAMA  •  1979  |  View Paper
The basic lesions of cardiomyocytes in anthracycline-induced cardiomyopathy are the lytic alterations and subsegmental contractures; in contrast, combined use of doxorubicin and epinephrine provoked degree II and III contractures.
Bulletin of Experimental Biology and Medicine  •  2019  |  View Paper
EPI and MEN 10755 were approximately 18% (P<0.05) or approximately 80% (P<0.001) less inhibitory than DOX , respectively.
British journal of pharmacology  •  2001  |  View Paper
The decrease in tumor doxorubicin concentration to low-dose (5 micrograms) and high-dose (15-50 micrograms) epinephrine suggests that intraarterial epinephrine limits doxorubicin uptake by tumor.
The Journal of surgical research  •  1987  |  View Paper