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“Catecholamine determinations showed that the administration of doxorubicin under hyperthermic conditions increased the liberation of both epinephrine and norepinephrine.”
British journal of pharmacology • 2001 | View Paper
“The decrease in tumor doxorubicin concentration to low-dose (5 micrograms) and high-dose (15-50 micrograms) epinephrine suggests that intraarterial epinephrine limits doxorubicin uptake by tumor.”