Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Epinephrine and Dextran

supplement:

Epinephrine

drug:

Dextran

Research Papers that Mention the Interaction

The addition of dextran caused a significant reduction in the absorption of both adrenaline and lignocaine from the injection site.
British journal of anaesthesia  •  1988  |  View Paper
The concentrations of nonadrenaline and adrenaline, were depressed (P < 0.05) by DEX and TR at 60 and 90 min of exercise.
European Journal of Applied Physiology and Occupational Physiology  •  1997  |  View Paper
Treatment of the jejunum with Epi resulted in significant increase in absorption of dextran in a dose-dependent fashion.
We evaluated the ability of Epi to enhance absorption of macromolecules using dextran (Mw 4000 Da), which is poorly absorbed from the intestine, as a model compound in situ in a closed loop of the rat jejunum.
Journal of controlled release : official journal of the Controlled Release Society  •  2005  |  View Paper
Inclusion of adrenaline , 5 μg/ml, in solutions containing prilocaine and Dx significantly prolonged the duration of the most profound degrees of IONB and of SA.
Acta anaesthesiologica Scandinavica  •  1988  |  View Paper
Dextran administered intravenously prior to the infusion of adrenalin or physiological saline alone prevented parenchymal lesions.
Scandinavian journal of urology and nephrology  •  1974  |  View Paper
The quantity of histamine released by dextran was reduced about 50% by the presence of isoproterenol (10-8 M), epinephrine (10-7 M) or norepinephrine (10-6 M).
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1972  |  View Paper