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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Dexmedetomidine

Research Papers that Mention the Interaction

Dexmedetomidine also prevented an increase in plasma epinephrine concentration following tourniquet inflation (p = 0.003).
Journal of clinical anesthesia  •  1994  |  View Paper
DEX infusion during the perioperative period inhibited release of epinephrine , norepinephrine, and cortisol; decreased blood glucose, interleukin (IL)-6, tumour necrosis factor-α, and C-reactive protein; and increased interleukin-10 in surgical patients.
British journal of anaesthesia  •  2019  |  View Paper
DEX administration and higher DEX concentrations attenuated lorazepam administration in the short-term and suppressed EPI.
DEX utilization suppressed EPI (r = -0.57, p = 0.004).
Alcohol  •  2015  |  View Paper
Dexmedetomidine inhibited the release of NE and E to induce their decline in blood.
European Journal of Clinical Pharmacology  •  2015  |  View Paper
Relatively recent … that dexmedetomidine is able to … norepinephrine and epinephrine concentration in approximately 50%, decreases brain blood flow by directly acting on post-synaptic alpha 2 receptors, decreases CSF pressure … suffering and effectively decreases brain metabolism and intracranial pressure and also, able to decrease injury caused by focal ischemia.
Middle East journal of anaesthesiology  •  2011  |  View Paper
Relatively recent … that dexmedetomidine is able to … norepinephrine and epinephrine concentration in approximately 50%, decreases brain blood flow by directly acting on post-synaptic alpha 2 receptors, decreases CSF pressure … suffering and effectively decrease brain metabolism and intracranial pressure and also, able to decrease injury caused by focal ischemia.
Middle East journal of anaesthesiology  •  2011  |  View Paper
OBJECTIVE Among the drugs for reducing hyperdynamic effects, dexmedetomidine and remifentanil are expected to blunt the acute hemodynamic responses after intranasal injection of epinephrine.
American journal of rhinology & allergy  •  2020  |  View Paper
Dex , imidazoline, yohimbine, and rauwolscine reduced the increases in contraction tension induced by the receptor stimulant adrenaline.
BMC Anesthesiology  •  2019  |  View Paper
In this study, we compared the duration of nerve block between dexmedetomidine and epinephrine as an adjuvant to 1% mepivacaine in infraclavicular brachial plexus block.
Korean journal of anesthesiology  •  2014  |  View Paper
Moreover, we found that DEX can prolong the local anesthetic duration of lidocaine as much as 1:80,000 epinephrine , up to 35 minutes after injection.
Anesthesia progress  •  2017  |  View Paper
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