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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Desoxycorticosterone Acetate

Research Papers that Mention the Interaction

On the other hand, studies in this …, 23) indicate that the administration of DCA to the rat induces a relative state of adrenocortical insufficiency by inhibiting the output of pituitary adrenocorticotropic …) and by antagonizing, at a target-cell level, the action of the ACTH-induced secretion of the adrena...
The Journal of clinical endocrinology and metabolism  •  1952  |  View Paper
Even the administration of desoxycorticosterone acetate (DCA) or adrenal cortical extracts will only maintain a normal response to hydration for a short period of time (Gaunt, 1944; Gaunt, Liling and Cordsen, 1945; Hays and Mathieson, 1945), although injections of epinephrine will increase the diuresis.
Endocrinology  •  1952  |  View Paper
That the uptake system was readily saturated was suggested by the observation that the sensitising actions of DOCA were decreased by procedures which decreased the potencies of epinephrine and isoprenaline, namely, phentolamine, and doses of isoprenaline eliciting constriction via alpha-stimulation, respectively.
Blood vessels  •  1978  |  View Paper