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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
supplement:
Epinephrine
drug:
Desflurane
Research Papers that Mention the Interaction
“BACKGROUND A rapid increase in the end-tidal concentration of desflurane to greater than 1 MAC transiently increases heart rate, arterial blood pressure, and circulating epinephrine and vasopressin concentrations.”
Fentanyl, Esmolol, and Clonidine Blunt the Transient Cardiovascular Stimulation Induced by Desflurane in Humans“BACKGROUND Large (0.5-1.0 MAC), rapid increases of desflurane to concentrations greater than 5% can transiently increase heart rate, mean arterial blood pressure (MAP), sympathetic nerve activity, and plasma epinephrine concentration.”
“ CONCLUSIONS Small (1%) increases in desflurane concentration to and greater than 6% can transiently increase heart rate, mean arterial pressure, and plasma epinephrine concentration.”
“The 1% increases in desflurane concentration to greater than 5% also transiently increased plasma epinephrine concentrations but not vasopressin concentration or plasma renin activity in those volunteers in whom MAP increased.”
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