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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epinephrine
drug:
Chloroprocaine
Research Papers that Mention the Interaction
“ Chloroprocaine and, to a lesser degree, lidocaine, produced marked attenuation of intubation-induced increases in plasma concentration of epinephrine and norepinephrine.”
Intravenous Chloroprocaine Attenuates Hemodynamic Changes Associated with Direct Laryngoscopy and Tracheal Intubation“The duration of the effect of chloroprocaine was substantially shorter than bupivacaine, but with this short‐lasting anesthetic the duration was prolonged by the addition of adrenalin.”
“CONCLUSIONS: Epidural anaesthesia using chloroprocaine with adrenaline has a quick onset and moderate duration and is an attractive alternative to lidocaine and adrenaline or chloroprocaine alone for caesarean section.”
“Previous work in pregnant ewes demonstrated a transient but significant (14 per cent) decrease in uterine blood flow when 2-chloroprocaine with epinephrine (10 μg/ml) was used.”
“ 2-Chloroprocaine 1.34 mg/kg, with epinephrine 0.2 microgram/kg, significantly decreased UBFV through 2 min.”
“The authors conclude that iv administration of 2-chloroprocaine with epinephrine significantly decreased UBFV in pregnant guinea pigs.”
The effect of intravenously administered 2-chloroprocaine upon uterine artery blood flow velocity in gravid guinea pigs.“Except for a transient 14 per cent decrease in uterine blood flow in the ewes receiving 2-chloroprocaine with epinephrine , uterine blood flow remained near control values and was sufficient at all times to maintain stable fetal acid-base and blood gas values.”
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