Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Epinephrine and Chloroprocaine

Research Papers that Mention the Interaction

Chloroprocaine and, to a lesser degree, lidocaine, produced marked attenuation of intubation-induced increases in plasma concentration of epinephrine and norepinephrine.
Anesthesia and analgesia  •  2000  |  View Paper
The duration of the effect of chloroprocaine was substantially shorter than bupivacaine, but with this short‐lasting anesthetic the duration was prolonged by the addition of adrenalin.
Acta obstetricia et gynecologica Scandinavica  •  1983  |  View Paper
CONCLUSIONS: Epidural anaesthesia using chloroprocaine with adrenaline has a quick onset and moderate duration and is an attractive alternative to lidocaine and adrenaline or chloroprocaine alone for caesarean section.
The Journal of international medical research  •  2012  |  View Paper
Previous work in pregnant ewes demonstrated a transient but significant (14 per cent) decrease in uterine blood flow when 2-chloroprocaine with epinephrine (10 μg/ml) was used.
Anesthesiology  •  1981  |  View Paper
2-Chloroprocaine 1.34 mg/kg, with epinephrine 0.2 microgram/kg, significantly decreased UBFV through 2 min.
The authors conclude that iv administration of 2-chloroprocaine with epinephrine significantly decreased UBFV in pregnant guinea pigs.
Anesthesiology  •  1989  |  View Paper
Except for a transient 14 per cent decrease in uterine blood flow in the ewes receiving 2-chloroprocaine with epinephrine , uterine blood flow remained near control values and was sufficient at all times to maintain stable fetal acid-base and blood gas values.
Anesthesiology  •  1976  |  View Paper