Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Epinephrine and Benoxinate



Research Papers that Mention the Interaction

After adding epinephrine, oxybuprocaine was much faster, reaching its maximal blockade, than proxymetacaine or lidocaine (P < 0.01).
Coadministration of proxymetacaine, oxybuprocaine , or lidocaine with epinephrine produced a synergistic analgesic effect and prolonged the cutaneous analgesic effect.
The use of epinephrine augmented the potency and prolonged the duration of proxymetacaine, oxybuprocaine , and lidocaine as an infiltrative anesthetic.
Regional Anesthesia & Pain Medicine  •  2016  |  View Paper