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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Epinephrine and Atipamezole



Research Papers that Mention the Interaction

Functionally, in comparison with yohimbine, an almost threefold lower concentration of atipamezole inhibited adrenaline (5 microM)-induced platelet aggregation.
Thrombosis research  •  2000  |  View Paper
Significant analgesic effects were noted for at least 4 h. The analgesic effect of intraspinal dexmedetomidine or epinephrine was blocked by systemic pretreatment with the alpha 2-adrenoceptor antagonists, yohimbine and atipamezole , but not with the alpha 1-adrenoceptor antagonist, prazosin.
European journal of pharmacology  •  1996  |  View Paper
Central administration of atipamezole also decreased the AD of epinephrine , while L-659,066, even if administered centrally, did not affect the AD of epinephrine in the presence of halothane.
Anesthesiology  •  1993  |  View Paper