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Last Updated: 2 months ago

Possible Interaction: Epinephrine and Ascorbate

supplement:

Epinephrine

supplement:

Ascorbate

Research Papers that Mention the Interaction

For example, ascorbate rapidly reduces cytochrome b561 from adrenal medullary chromaffin vesicles.
The American journal of clinical nutrition  •  1991  |  View Paper
The effect of ascorbate was largely due to the fact that it increased the phosphorus metabolism of the adrenals of rats maintained at room temperature.
Canadian journal of biochemistry and physiology  •  1956  |  View Paper
Ascorbate and adrenaline were highly synergistic in their effects, provided that the ascorbate was present from the start of culture; the response to adrenaline strongly reflected the degree of ascorbate stimulation.
The Journal of endocrinology  •  1988  |  View Paper
The epinephrine and norepinephrine contents of chromaffin cell cultures supplemented with ascorbate for 7 days were increased approximately 10% compared to cultures without added ascorbic acid; ascorbate had no effect on chromaffin cell opioid peptide levels.
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  1983  |  View Paper
When compared to adrenal enzyme activities in animals on high dietary levels of ascorbate, the adrenals of animals on 2.4 mg of ascorbate per day expressed 50% increase in the activities of acid phosphatase, arylsulfatase A, and arylsulfatase B (p less than 0.02).
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition  •  1982  |  View Paper
Ascorbate (0.5 mM) inhibited ACTH-induced cyclic [14C]AMP formation in adrenal cells isolated from Vitamin E-deficient rats but had no effect in the control cells.
Biochimica et biophysica acta  •  1975  |  View Paper
Reducing agents ascorbate , sodium bisulfite) diminished the effects of epinephrine , but did not alter the effects of adrenochrome.
Endocrinology  •  1970  |  View Paper
Epinephrine inhibited lipid peroxidation produced by ascorbate.
The Journal of biological chemistry  •  1969  |  View Paper