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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Epinephrine and 8-Chloro-Cyclic Adenosine Monophosphate

Research Papers that Mention the Interaction

In this species, epinephrine appeared to exert its action on hepatic glycogenolysis by altering the cytosolic concentrations of both adenosine 3',5'-cyclic monophosphate (cAMP) and Ca2+.
The American journal of physiology  •  1988  |  View Paper
Our biochemical studies demonstrated that epinephrine could increase adenosine 3',5'-cyclic monophosphate levels markedly in cultured retinal cells.
Taken together, the results indicate that the facilitatory effect of epinephrine is mediated via a beta adrenoceptor and may involve an increase in adenosine 3',5'-cyclic monophosphate levels.
The accumulation of adenosine 3',5'-cyclic monophosphate induced by epinephrine could be blocked by propranolol, but not by yohimbine nor haloperidol.
Neuroscience  •  1987  |  View Paper
However, aqueous humor c-AMP was significantly elevated 30 min after epinephrine treatment, peaked between 60 and 240 min, and declined to baseline by 6 hr before a significant ocular hypotensive response was noted.
Experimental eye research  •  1981  |  View Paper