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Last Updated: 2 months ago

Possible Interaction: Epinephrine and 8-Chloro-Cyclic Adenosine Monophosphate

Research Papers that Mention the Interaction

Consistent with the dual channel activation, epinephrine treatment resulted in increases in both intracellular cAMP and Ca(2+).
American journal of physiology. Lung cellular and molecular physiology  •  2014  |  View Paper
Catecholamines (norepinephrine, epinephrine ) and their analogs (isoproterenol, phenylephrine, 6-fluoronorepinephrine) dose-dependently stimulated endothelial production of cAMP.
Metabolic Brain Disease  •  2005  |  View Paper
Although SQ22536, dideoxyadenosine, and epinephrine reduced the cAMP levels, only epinephrine could mimic the P2TAC receptor mediated signaling events, suggesting that reduction in basal cAMP levels does not directly contribute to ADP-induced platelet activation.
Thrombosis and haemostasis  •  1999  |  View Paper
cAMP response to stimulation by epinephrine , which was obtained as the area under the curve (AUC) for plasma cAMP concentration divided by the AUC for plasma concentration of epinephrine, was more pronounced during surgery (mean ratio 3.5) than in the control situation (ratio 1.4; P < 0.02).
British journal of anaesthesia  •  1998  |  View Paper
Epinephrine inhibits lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF) production by increasing intracellular cAMP concentrations.
Journal of leukocyte biology  •  1997  |  View Paper
Epinephrine (10(-6) M) rapidly stimulated cAMP with a peak between 2.5 and 5 min, which gradually returned to basal levels over 3-4 hr.
Biochemical pharmacology  •  1994  |  View Paper
When the cells were exposed to EPI (1 nM-10 microM) for 72 h, a dose-dependent increase of cAMP levels with a maximum of 60% above basal levels.
Scandinavian journal of clinical and laboratory investigation  •  1993  |  View Paper
In ghosts prepared from normal RBC, norepinephrine and epinephrine significantly increased intracellular cAMP concentrations; in these ghosts, relative ionic chloride permeability (permeability of chloride/permeability of potassium (PCI/PK)), but not PNa/PK (permeability of sodium/permeability of potassium), was significantly increased.
Journal of the American Society of Nephrology : JASN  •  1993  |  View Paper
Epinephrine at 10(-6) M caused abnormal cytokinesis and cell retraction, inhibited mitosis and phagocytosis, and induced a 4- to 5-fold increase in cAMP.
Lens and eye toxicity research  •  1989  |  View Paper
Epinephrine infusion increased cAMP in muscle by 3-fold and transformed 80% of phosphorylase to the a form.
Medicine and science in sports and exercise  •  1988  |  View Paper
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