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“In this species, epinephrine appeared to exert its action on hepatic glycogenolysis by altering the cytosolic concentrations of both adenosine 3',5'-cyclic monophosphate (cAMP) and Ca2+.”
The American journal of physiology • 1988 | View Paper
“Our biochemical studies demonstrated that epinephrine could increase adenosine 3',5'-cyclic monophosphate levels markedly in cultured retinal cells.”
“Taken together, the results indicate that the facilitatory effect of epinephrine is mediated via a beta adrenoceptor and may involve an increase in adenosine 3',5'-cyclic monophosphate levels.”
“The accumulation of adenosine 3',5'-cyclic monophosphate induced by epinephrine could be blocked by propranolol, but not by yohimbine nor haloperidol.”
“However, aqueous humor c-AMP was significantly elevated 30 min after epinephrine treatment, peaked between 60 and 240 min, and declined to baseline by 6 hr before a significant ocular hypotensive response was noted.”