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Last Updated: 3 years ago

Possible Interaction: Epigallocatechin Gallate and Rosuvastatin

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supplement:

Epigallocatechin Gallate

drug:

Rosuvastatin

Research Papers that Mention the Interaction

“This study demonstrated that co-administration of EGCG reduces the systemic exposure of rosuvastatin by 19%, and pretreatment of EGCG can eliminate that effect of co-administration of EGCG.”

Effect of epigallocatechin-3-gallate, major ingredient of green tea, on the pharmacokinetics of rosuvastatin in healthy volunteers

Drug design, development and therapy • 2017 | View Paper

“ EGCG may be the main ingredient of green tea that affects the pharmacokinetic parameters of rosuvastatin.”

“However, in the EGCG group, the uptake and transport of rosuvastatin were decreased by 22.62% and 44.19%, respectively (p<0.050).”

Effect of Green Tea and (-)-epigallocatechin Gallate on the Pharmacokinetics of Rosuvastatin.

Current drug metabolism • 2020 | View Paper

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