Possible Interaction: Epigallocatechin Gallate and Kaempferol

“Taken together, our results for the first time suggest that the combination of luteolin and EGCG has synergistic/additive growth inhibitory effects and provides an important rationale for future chemoprevention trials of head and neck and lung cancers.”

“Herein, we demonstrate that micromolar combinations of EGCG and a second polyphenol, luteolin , synergistically inhibit TGF-β-induced myofibroblast phenotypes in prostate fibroblast cell lines, as observed primarily by potentiation of fibronectin expression.”

“The ability of EGCG and luteolin to synergistically target myofibroblasts suggests that combined clinical use of these compounds could prevent or reverse cancer progression through targeting the tumor microenvironment, in addition to the tumor itself.”

“Results showed that kaempferol , quercetin, and myricetin accelerated the oxidation of EGCG and made the model solution browning.”