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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“ EGCG induced an intracellular increase in reactive oxygen species and GSSG , both of which were also inhibited by NAC, and the decreased synthesis of glutathione rendered the cell susceptible to EGCG-induced apoptosis.”
Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.“… EGCG significantly decreased H2O2-reduced cell viability and apoptotic cells with DNA damage, restored … capacity (T-AOC), glutathione peroxidase (GSH-PX), superoxide dismutase (SOD), glutathione (GSH), and glutathione disulfide (GSSG), and suppressed the increase in intracellular reactive oxygen species (… (NOS), malondialdehyde (MDA), lipid peroxide (LPO), and protein carbonyl (Carbonyl).”
Protective Effect of Epigallocatechin-3-Gallate in Hydrogen Peroxide-Induced Oxidative Damage in Chicken Lymphocytes“… EGCG significantly attenuated … of oxidized/total glutathione ratio (281+/-66 nmol/g and 0.48+/-0.03) as compared to the those (415+/-46 nmol/g and 0.64+/-… and 0.61+/-0.06) of the control group and the EGCG 25 mg/kg treated group (p<0.05).”
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