Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Epigallocatechin Gallate and Ascorbate

supplement:

Ascorbate

Research Papers that Mention the Interaction

The DNA-damaging ability of EGCG , but not curcumin, was hindered by either ascorbate or NAC, which was also shown in HT29 and SW480 colon cancer cells.
Thus, these findings suggest that ascorbate and NAC interfere with the ability of EGCG , but not curcumin, to kill HCT116 cells.
Free radical research  •  2014  |  View Paper
EGCG also effectively scavenged the ascorbate and gallate radicals, more efficiently than other compounds.
Anticancer research  •  2001  |  View Paper
For 50% inhibition of tyrosine nitration, the respective concentrations were 1.4, 4.6 or 0.11 mM. Thus, (−)-epigallocatechin gallate is a significantly better inhibitor of both reactions than either ascorbate or glutathione.
Experientia  •  2005  |  View Paper