supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago
supplement:
Epigallocatechin Gallate
drug:
Afimoxifene
Research Papers that Mention the Interaction
“ EGCG at a dose of 10 mg/kg significantly increased … concentration–time curve (P<0.05, 40.3%) of 4-hydroxytamoxifen , but the metabolite–parent ratio of 4-hydroxytamoxifen was also significantly altered (P<0.… of EGCG), implying that the formation of 4-hydroxytamoxifen was considerably affected by EGCG.”
Effects of epigallocatechin gallate on the oral bioavailability and pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback