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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Epicatechin
supplement:
Epigallocatechin
Research Papers that Mention the Interaction
“ EC along with another cancer preventive agent sulindac also synergistically enhanced apoptosis in PC-9 cells induced by EGCG.”
Green tea and cancer chemoprevention.“ (-)-Epicatechin enhanced apoptosis, growth inhibition of PC-9 cells, and inhibition of tumor necrosis factor-alpha release from BALB/c-3T3 cells by EGCG and other tea polyphenols with a galloyl moiety in a dose-dependent manner.”
“The ability of gallate catechin such as (-)-epigallocatechin gallate (EGCG) and (-)-epicatechin gallate (ECG) to increase the cellular accumulation of EC was greater than that of nongallate catechins.”
“Furthermore, the synergistic effect of EC with EGCG on the induction of apoptosis was specifically canceled by catalase treatment, suggesting that the synergism involves the extracellular production of reactive oxygen species.”
“In addition, (-)-epicatechin (EC) had a major synergistic effect on the induction of apoptosis in MKN-45 cells treated with EGCG ; however it had little effect on the inhibition of cell growth induced by EGCG.”
“Similarly, the combined treatment with 5 microM EGC and 5 microM of C, EC , EGCG or ECG also reduced the cytotoxicity.”
Synergistic effect of green tea polyphenols on their protection against FK506-induced cytotoxicity in renal cells.“The synergistic effects of (-)-epicatechin (EC) with (-)-epigallocatechin gallate (EGCG) on AH109A invasion were demonstrated.”
“In particular, incubation of epicatechin with epigallocatechin with tyrosinase gave a high, stable theaflavin content.”
Altering the phenolics profile of a green tea leaves extract using exogenous oxidases.“(-)-Epigallocatechin (EGC) and (-)-epicatechin (EC) were found to be the main contributors for the sweet aftertaste, based on a trial compatibility with EGCG, ECG, EGC, and EC monomers, and a synergistic action between EGC and EC to sweet aftertaste was observed.”
“Determining the TAC of individual tea catechins showed that ORAC of epicatechin was seven-fold higher than that of epigallocatechin gallate; on the contrary, epigallocatechin gallate showed significantly (P < 0.05) stronger DRSC activity than epicatechin.”
“For delta-tocopherol, a synergistic antioxidant effect was observed in the presence of both EC and EGCG , whereas antioxidant activity for alpha-, beta- and gamma-tocopherol was decreased by addition of EC and EGCG.”
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