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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Epicatechin
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“The half-life of EGCG (5.0-5.5 h) seemed to be higher than the half-life of EGC or EC (2.5-3.4 h).”
Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers.“The combination of only 1 μg/mL of epicatechin plus 10 μg/mL of EGCG displayed synergistic effects on growth inhibition and induction of apoptosis.”
“The amounts of EGCg required to inhibit by both criteria was reduced 10 times by combination with inactive catechins such as (-)-epicatechin (EC), (-)-epigallocatechin (EGC) or (-)-epicatechin-3-gallate (ECG).”
“ (-)-Epicatechin-3-gallate , had lower activities, and (-)-epicatechin was even less effective.”
“ EGCG potently inhibited proton currents with an IC(50) of 3.7 μM. Other tea catechins, (-)-epigallocatechin, (-)-epicatechin and (-)-epicatechin-3-gallate, were far less potent than EGCG.”
(-)-Epigallocatechin-3-gallate inhibits voltage-gated proton currents in BV2 microglial cells.“Although other polyphenols present in GTPP, particularly epigallocatechin and epicatechin , lack this activity, they synergistically promoted this action of EGCG.”
“ (-)-Epicatechin exhibited synergistic effects with (-)-epigallocatechin-3-gallate , (-)-epicatechin-3-gallate, and theaflavins against AH109A cell proliferation.”
“Adding EGCG , during the blue light illumination treatment of EC decreased photolytic formation, suggesting that gallate-type catechins can suppress the photosensitive oxidation of EC.”
Effects of Epigallocatechin Gallate on the Stability of Epicatechin in a Photolytic Process
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