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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Enoxacin
supplement:
Guanidines
Research Papers that Mention the Interaction
“The basolateral-to-apical transport of CPFX was sensitive to the pH of … medium, and increased in an acidic pH. Enoxacin (ENX) as well as guanidine , inhibited the basolateral-to-apical transport …, and the inhibitory effect of ENX was sensitive to the pH of … apical side of the monolayers.”
The transport of ciprofloxacin in cultured kidney epithelial cells LLC-PK1.“Cimetidine and guanidine inhibited the uptake of ENX , whereas TEA and NMN did not.”
“The apical to basolateral flux of ENX was inhibited by cimetidine and guanidine , whereas it was not inhibited by TEA and NMN.”
“The basolateral to apical flux of ENX was remarkably inhibited by guanidine , whereas it was not inhibited by TEA, NMN and cimetidine.”
“ ENX uptake was inhibited by probenecid, cimetidine, guanidine and disopyramide, suggesting that ENX might possess an affinity for both anionic and cationic transport mechanisms.”
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