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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Enoxacin and Guanidines

supplement:

Guanidines

Research Papers that Mention the Interaction

The basolateral-to-apical transport of CPFX was sensitive to the pH of … medium, and increased in an acidic pH. Enoxacin (ENX) as well as guanidine , inhibited the basolateral-to-apical transport …, and the inhibitory effect of ENX was sensitive to the pH of … apical side of the monolayers.
Biological & pharmaceutical bulletin  •  1997  |  View Paper
Cimetidine and guanidine inhibited the uptake of ENX , whereas TEA and NMN did not.
The apical to basolateral flux of ENX was inhibited by cimetidine and guanidine , whereas it was not inhibited by TEA and NMN.
The basolateral to apical flux of ENX was remarkably inhibited by guanidine , whereas it was not inhibited by TEA, NMN and cimetidine.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan  •  1996  |  View Paper
ENX uptake was inhibited by probenecid, cimetidine, guanidine and disopyramide, suggesting that ENX might possess an affinity for both anionic and cationic transport mechanisms.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan  •  1995  |  View Paper