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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Enflurane
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“Conclusions γ-Aminobutyric acid type A receptors containing the α1 subunit participate in the inhibition of the righting reflexes by isoflurane and enflurane.”
Effect of Isoflurane and Other Potent Inhaled Anesthetics on Minimum Alveolar Concentration, Learning, and the Righting Reflex in Mice Engineered to Express α1 γ-Aminobutyric Acid Type A Receptors Unresponsive to Isoflurane“ Enflurane (4%) was antagonistic to both IVM and GABA.”
“Halothane (0.86 … mM), and enflurane (1.89 mM), each equivalent to the respective 2 minimum alveolar …, augmented the sustained current evoked by 3 times 10−6 M GABA to 330‐350% of control and the peak current evoked … 10−5 M of GABA to 136‐145% of control.”
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