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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Enalapril and Glutathione



Research Papers that Mention the Interaction

Pretreatment with COLF and enalapril increased the tissue GSH and p65NFkB levels (p < 0.05) and significantly reduced serum CRP, AOPP, LDH and CKMB.
Journal of basic and clinical physiology and pharmacology  •  2020  |  View Paper
Enalapril treatment significantly enhanced the total antioxidant status (TAS) (… < 0.001), reduced the oxidized glutathione ratio ( GSH : GSSG) (P < 0.001), and reduced to thibarbituric acid reactive substances (TBARS) (P < 0.001) and protein carbonyl content (PCO) (P < 0.001), which thus reduced the oxidative stress in the heart.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer  •  2017  |  View Paper
Enalapril also augmented anti-oxidant activity in ischaemic brain tissue by increasing GSH concentrations and significantly (P < 0.05) attenuating the increased MDA levels in response to ischaemia.
Clinical and experimental pharmacology & physiology  •  2014  |  View Paper
Pre-treatment of enalapril or valsartan for 14 days reduced (p < 0.001) serum AST and plasma MDA levels and increased the concentration of erythrocyte GSH in enalapril pre-treated group (p < 0.01) and in valsartan pre-treated group (p < 0.05).
Bangladesh Medical Research Council bulletin  •  2014  |  View Paper
Enalapril , paricalcitol or the two in combination all protected against this reduction in glutathione.
American Journal of Nephrology  •  2008  |  View Paper
Enalapril increased GSSG + GSH content (P < 0.05) in erythrocytes (147%), brain (112%), and lung (67%), and captopril increased GSSG + GSH content in erythrocytes (190%) and brain (132%).
American journal of physiology. Regulatory, integrative and comparative physiology  •  2000  |  View Paper
EN produced a dose-dependent reduction in intracellular glutathione ( GSH ) concentration.
Toxicology letters  •  1991  |  View Paper