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Last Updated: 2 years ago

Possible Interaction: Emodin and Zidovudine

supplement:

Emodin

Research Papers that Mention the Interaction

Furthermore, the combination of emodin and AZT increased apoptosis in K562 cells (P<0.05).
The results demonstrated that AZT enhanced the inhibitory effect of emodin in K562 cells.
Oncology reports  •  2019  |  View Paper
din co ca n synergistically inhibit the proliferation, induce cell apoptosis, and down regulate the expression of NF-κB, BCL-2 and TGF-β mRNA and proteins in … of synergistic effect may be associated with inhibiton of BCL-2 activation and down-regulation of the expression of NF-κB, and TGF-β.
Zhongguo shi yan xue ye xue za zhi  •  2015  |  View Paper
The combination of emodin and AZT had considerable synergistic inhibitory effects on proliferation of normal KG-1a cells and nonspecific control(KG-1a NC) cells, but the synergistic effects disappeared after Egr-1 gene silencing.
Zhongguo shi yan xue ye xue za zhi  •  2015  |  View Paper
Abstract Context: Previous studies have demonstrated that both 3′-azido-3′-deoxythymidine AZT ) and emodin , a traditional chemotherapy agent, can inhibit the growth of many types of cancer cells.
All examined combinations of AZT and emodin yielded a synergetic effect (CI < 1).
Discussion and conclusion: These results show a synergistic growth-inhibitory effect of AZT and emodin in K562/ADM cells, which is achieved through S phase arrest.
Results: The growth suppression of emodin was dramatically enhanced by AZT in K562/ADM cells.
Pharmaceutical biology  •  2013  |  View Paper