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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Emodin and Serotonin

supplement:

Emodin

Research Papers that Mention the Interaction

In the presence of emodin (10 microM), the contractile responses of rat aorta to phenylephrine, serotonin and potassium chloride were depressed.
European journal of pharmacology  •  1991  |  View Paper
KEY RESULTS Emodin , an active ingredient of Polygonum multiflorum extract, inhibited phenylephrine-induced vasoconstriction in rat isolated thoracic aorta, and inhibited vasoconstriction induced by 5-HT and endothelin-1.
KEY RESULTS Emodin , an active ingredient of Polygonum multiflorum extract, inhibited phenylephrine-induced vasoconstriction in rat isolated thoracic aorta, and inhibited vasoconstriction induced by 5-HT and endothelin-1.
British journal of pharmacology  •  2014  |  View Paper
In parallel, emodin also attenuated methamphetamine-induced increases in dopamine and its metabolites and decreases in serotonin and its metabolites.
Pharmacology Biochemistry and Behavior  •  2010  |  View Paper