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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
supplement:
Emodin
drug:
Phenylephrine
Research Papers that Mention the Interaction
“We additionally present evidence that emodin inhibited phenylephrine (PE) and phorbol myristate acetate (PMA)-induced hypertrophy in neonatal rat ventricular myocytes (NRVMs).”
Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy.“In the presence of emodin (10 microM), the contractile responses of rat aorta to phenylephrine , serotonin and potassium chloride were depressed.”
Vasorelaxant effect of emodin, an anthraquinone from a Chinese herb.“In contrast, post-treatment with emodin following phenylephrine stimulation potently suppressed tonic tension in rat aortic rings.”
Emodin inhibits tonic tension through suppressing PKCδ‐mediated inhibition of myosin phosphatase in rat isolated thoracic aorta
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