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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Emodin and Paclitaxel

supplement:

Emodin

Research Papers that Mention the Interaction

Conclusion: Our findings indicated that emodin could significantly enhance antitumor effect of PTX in vitro and in vivo.
Results: Combination of emodin with PTX synergistically inhibited the proliferation of A549 cells in vitro.
Therefore, the combination of emodin with PTX may serve as a potential strategy for the treatment of patients with NSCLC.
Drug design, development and therapy  •  2019  |  View Paper
Furthermore, the combination of emodin and paclitaxel synergistically inhibited the anchorage-dependent and -independent growth of HER-2/neu-overexpressing breast cancer cells in vitro and synergistically inhibited tumor growth and prolonged survival in athymic mice bearing s.c.
Clinical cancer research : an official journal of the American Association for Cancer Research  •  1999  |  View Paper
Our results suggest the possibility of an innovative chemotherapeutic strategy that uses emodin in combination with paclitaxel to increase the sensitivity of tumor cells.
Oncology reports  •  2009  |  View Paper