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Last Updated: 2 months ago

Possible Interaction: Emodin and Nitric Oxide

supplement:

Emodin

Research Papers that Mention the Interaction

The results demonstrated that treatment with emodin treatment reduced the cytotoxicity of IL-1β and inhibited the expression of NO and PGE2 in rat chondrocytes.
Experimental and therapeutic medicine  •  2018  |  View Paper
Thereby, emodin modulates macrophage phagocytosis, migration, and NO production.
The Journal of Biological Chemistry  •  2016  |  View Paper
In addition, emodin significantly reduced ConA-induced nitric oxide (NO) production and the formation/release of TH1 (IL-2, IFNγ, TNFα) and TH17 (IL-6 and IL-17) cell cytokines, but induced those of TH2 (IL-4) and Treg (IL-10) cells.
Journal of immunotoxicology  •  2016  |  View Paper
Aloe-emodin resulted in significant activation of nitric oxide production.
International Journal of Antimicrobial Agents  •  2008  |  View Paper
On the other hand, inhibition effects on NO production from RAW 264.7 cells were enhanced and cytotoxic effects decreased by co-treatment with emodin and rhein.
Planta medica  •  2002  |  View Paper
RESULTS Emodin restored the cell … to 50 μM. Emodin … nitric oxide , IL-1α, IL-Ιβ, IL-6, GM-CSF, G-CSF, M-CSF, MCP-1, MIP-1a, MIP-Ιβ, MIP-… of signal transducer and activated transcription 1 (STAT1) in poly I:C-induced RAW 264.7 (P < 0.05).
RESULTS Emodin restored the … up to 50 μM. Emodin … nitric oxide , IL-1α, IL-Ιβ, IL-6, GM-CSF, G-CSF, M-CSF, MCP-1, MIP-1a, MIP-Ιβ, MIP-… of signal transducer and activated transcription 1 (STAT1) in poly I:C-induced RAW 264.7 (P < 0.05).
African journal of traditional, complementary, and alternative medicines : AJTCAM  •  2017  |  View Paper
Moreover, emodin decreased dramatically the LPS-induced production of NO and PGE2 as well as the protein expression and promoter activity of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2).
Neurochemical Research  •  2016  |  View Paper
Our results demonstrated that aloe-emodin dose-dependently inhibited inducible nitric oxide synthase (iNOS) mRNA expression and nitric oxide (NO) production at 5-40 microM. In addition, the levels of cyclooxygenase-2 (COX-2) mRNA and prostaglandin E2 (PGE2) production were suppressed by 40 microM aloe-emodin.
Bioscience, biotechnology, and biochemistry  •  2009  |  View Paper
Emodin markedly decreased the expression of PCNA in VSMC, increased NO , NOS and iNOS levels, and increased iNOS mRNA expression in VSMC.
Emodin markedly decreased the expression of PCNA in VSMC, increased NO , NOS and iNOS levels, and increased iNOS mRNA expression in VSMC.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica  •  2008  |  View Paper