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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Emodin and Interferons

supplement:

Emodin

Research Papers that Mention the Interaction

Intriguingly, emodin induced proteosomal degradation of epidermal growth factor receptor (EGFR)/EGFR variant III (EGFRvIII) by interfering with the association of EGFR/EGFRvIII with heat shock protein 90, resulting in the suppression of stemness pathways.
Stem cells and development  •  2015  |  View Paper
In addition, emodin significantly reduced ConA-induced nitric oxide (NO) production and the formation/release of TH1 (IL-2, IFNγ , TNFα) and TH17 (IL-6 and IL-17) cell cytokines, but induced those of TH2 (IL-4) and Treg (IL-10) cells.
Journal of immunotoxicology  •  2016  |  View Paper