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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Emodin and Glyburide

supplement:

Emodin

Research Papers that Mention the Interaction

(2) PRO (P < 0.05) or GLI (P < 0.01) partly abolished the inhibitory effect of emodin on jejunum smooth muscle.
2) PRO (P < 0.05) or GLI (P < 0.01) partly abolished the inhibitory effect of emodin on jejunum smooth muscle. (
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology  •  2014  |  View Paper
KEY RESULTS Basolateral addition of emodin induced a concentration-dependent increase in I(…) in colonic mucosa/submucosa preparations, EC(50) 75 µM. The effect of emodin was blocked … apically applied glibenclamide , a Cl(-) channel blocker, and by basolateral application of bumetanide, an inhibitor of the Na(+) -K(+) -2Cl(-) cotransporter.
KEY RESULTS Basolateral addition of emodin induced a concentration-dependent increase in …(SC) in colonic mucosa/submucosa preparations, EC(50) 75 µM. The effect of emodin was blocked … apically applied glibenclamide , a Cl(-) channel blocker, and by basolateral application of bumetanide, an inhibitor of the Na(+) -K(+) -2Cl(-) cotransporter.
British journal of pharmacology  •  2012  |  View Paper