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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Emodin
supplement:
Glutathione
Research Papers that Mention the Interaction
“One arose from direct adduction of EM with GSH , and the other was derived from M1.”
Chemical Reactivity of Emodin and Its Oxidative Metabolites to Thiols.“ AE was found to cause redox imbalance and deplete the intracellular-reduced glutathione ( GSH).”
“ GSH was also significantly higher after 0.2-1 μg/ml emodin exposure, indicating that cells failed to maintain their redox balance when compensating for the increased oxidative stress.”
The effect of emodin on cytotoxicity, apoptosis and antioxidant capacity in the hepatic cells of grass carp (Ctenopharyngodon idellus).“ Emodin pretreatment significantly reduced the levels of ALT, AST, and … hepatocellular damage and apoptosis; attenuated the exhaustion of GSH and SOD and the accumulation of MDA; and increased the expression of antioxidative enzymes, including … 2 (Nrf2), heme oxygenase 1 (HO-1), and NAD(P)H quinone dehydrogenase 1 (NQO1).”
Emodin Attenuates Acetaminophen-Induced Hepatotoxicity via the cGAS-STING Pathway.
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