supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Emodin
drug:
Fluorouracil
Research Papers that Mention the Interaction
“The combinatory use of AE and 5-fluorouracil (5-Fu) achieved significantly more cell death in A431 and SCC25 cells than only the use of AE or 5-Fu, likely via regulation of caspase-8, -9, and -3 expressions.”
The molecular effects of aloe-emodin (AE)/liposome-AE on human nonmelanoma skin cancer cells and skin permeation.“Moreover, emodin reduced 5-Fu resistant in CRC via downregulation of PI3K/Akt signaling.”
“RESULTS Em din no tably increased the anti-proliferation effect of 5-F u in SW480/5-Fu cells.”
Emodin reverses 5-Fu resistance in human colorectal cancer via downregulation of PI3K/Akt signaling pathway.“ AE can also enhance the anticancer efficacy of cisplatin, doxorubicin, docetaxel, and 5-fluorouracil ; however, its effects remain poorly characterized.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback