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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Emodin and Epirubicin

supplement:

Emodin

Research Papers that Mention the Interaction

Furthermore, the addition of emodin enhanced ADR and DNR intracellular accumulation and subcellular distribution in HL-60/ADR cells in dose-dependent manner.
Zhongguo shi yan xue ye xue za zhi  •  2013  |  View Paper
When emodin was added to the cell culture at the concentration of 10 μg/ml, the drug resistance was reduced from 21 folds to 2.86 folds for adriamycin , and from 11 folds to 1.79 folds for cisplatin.
Journal of Translational Medicine  •  2012  |  View Paper
The in vivo assay showed that emodin inhibited tumor growth, and suppressed the lung and liver metastasis of TNBC cells by decreasing the secretion of CCL5 in mice fed a high fat and sugar diet more efficiently when compared with epirubicin.
The results showed that emodin inhibited TNBC proliferation and invasion more efficiently than epirubicin when co‑cultured with adipocytes by downregulating the level of CCL5 in adipocyte supernatants; inhibiting the expression level of protein kinase B (AKT); and activating glycogen synthase kinase‑3i (GSK3) and β‑catenin.
International journal of molecular medicine  •  2018  |  View Paper