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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Emodin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Mechanism study indicated that aloe-emodin rapidly and reversibly decreased cytosolic Ca2+ (Ca2+[c]) concentration through enhancing the mitochondrial Ca2+ (Ca2+[m]) uptake.”
Aloe-emodin, a naturally occurring anthraquinone, is a highly potent mast cell stabilizer through activating mitochondrial calcium uniporter.“We demonstrate that AE repressed not only the phenotypes of Ca2+ induced calcification but also level of calcium in VSMCs.”
Aloe-emodin inhibits osteogenic differentiation and calcification of mouse vascular smooth muscle cells.“RESULT Em din co uld significantly inhibit levels of amylase, lipase and intracellular cal cium an d ER.”
“Under MODS …, emodin could still … the intracellular calcium ion concentration; this effect could be inhibited by heparin (inosamine triphosphate receptor inhibitor IP3 and ryanodine receptor inhibitor in MODS model … the calcium chelator EGTA and nifedipine (the specific cell membrane voltage dependent calcium channel blocker) showed no influence on it.”
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