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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Emodin
supplement:
Aloe Vera Whole
Research Papers that Mention the Interaction
“Furthermore, aloe emodin treatment led to a substantial enhancement of the conversion of light chain 3 (LC3)-l to LC3-ll and this increase was shown to follow aloe emodin dose-dependent pattern, thus indicating that aloe emodin may induce autophagy in addition to apoptosis.”
Aloe emodin exerts potent anticancer effects in MIAPaCa-2 and PANC-1 human pancreatic adenocarcinoma cell lines through activation of both apoptotic and autophagic pathways, sub-G1 cell cycle arrest and disruption of mitochondrial membrane potential (ΛΨm).“Our data also demonstrated that aloe emodin arrested the cell cycle in the S phase and promoted the loss of mitochondrial membrane potential in U87 cells that indicated the early event of the mitochondria-induced apoptotic pathway.”
“The anti-inflammatory effect of aloe-emodin was comparable to that of kaempferol and quercetin, indicating aloe-emodin as a possible key constituent responsible for the anti-inflammatory activity of aloe.”
Evaluation of Aloin and Aloe-Emodin as Anti-Inflammatory Agents in Aloe by Using Murine Macrophages“However, present work evidenced that molecular docking of aloe emodin modulates the anti-inflammatory activity, as well as expression of COX-2 (cyclooxygenase-2) in rodent.”
Anti-Inflammatory and Antiarthritic Activity of Anthraquinone Derivatives in Rodents“The results showed that aloe emodin inactivated all of the viruses tested except adenovirus and rhinovirus.”
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