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“Following treatment with aloe emodin (10, 40 and 80 µM) the early apoptotic cell percentage increased to 17.5, 39.6 and 58.8%, respectively, while late apoptotic cells percentage increased to 22.3, 27.6 and 37.2% respectively.”
Journal of B.U.ON. : official journal of the Balkan Union of Oncology • 2019 | View Paper
“Our data also demonstrated that aloe emodin arrested the cell cycle in the S phase and promoted the loss of mitochondrial membrane potential in U87 cells that indicated the early event of the mitochondria-induced apoptotic pathway.”
Journal of Asian natural products research • 2013 | View Paper
“However, present work evidenced that molecular docking of aloe emodin modulates the anti-inflammatory activity, as well as expression of COX-2 (cyclooxygenase-2) in rodent.”
International journal of inflammation • 2014 | View Paper
“ Aloe emodin and chrysophanol were remarkably increased by the SA treatment, more than 10-11 and 5-13 fold as compared with untreated control, respectively.”
Antimicrobial Agents and Chemotherapy • 1991 | View Paper
“The anti-inflammatory effect of aloe-emodin was comparable to that of kaempferol and quercetin, indicating aloe-emodin as a possible key constituent responsible for the anti-inflammatory activity of aloe.”
Bioscience, biotechnology, and biochemistry • 2009 | View Paper
“We have studied the inhibitory effect of aloe emodin on hepatic stellate cells activation and proliferation, as these cells play a key role in the pathogenesis of hepatic fibrosis.”