Discover Supplement-Drug Interactions
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2 months ago
Possible Interaction: Ellagic Acid and O(6)-Benzylguanine
Research Papers that Mention the Interaction
“HPLC analysis of DNA hydrolysates showed that
caused a dose-dependent 36-84% decrease in
but only a 20% decrease in the 7-methylguanine adduct.”
Inhibition of N-methyl-N-nitrosourea-induced mutagenicity and DNA methylation by ellagic acid.
Proceedings of the National Academy of Sciences of the United States of America • 1986 |
“In some model systems,
has been reported to selectively decrease the mutagenic DNA adduct O6-methylguanine (
) when compared to the cytotoxic DNA adduct N7-methylguanine (N7MG).”
Ellagic acid embryoprotection in vitro: distribution and effects on DNA adduct formation.
Teratology • 1993 |
caused a dose-dependent decrease in the formation of N7-methylguanine and
Inhibition of N-nitrosobenzylmethylamine metabolism and DNA binding in cultured rat esophagus by ellagic acid.
Carcinogenesis • 1988 |
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