“ Ellagic acid dose-dependently lowered caspase-3 activity and … 1 % declined activity and protein level of NF-κB. Doxorubicin treatment also up-regulated cardiac expression of p-p38, p-ERK 1/2 and p-… 1 % suppressed p-p38 expression and at 1 % down-regulated p-ERK 1/2 expression.”
“These findings suggest that ellagic acid is a potent cardiac protective agent against doxorubicin.”