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Last Updated: 2 years ago

Possible Interaction: Eicosapentaenoic Acid and Phospholipids

Research Papers that Mention the Interaction

However, in rats and humans, we have found that low doses of EPA actually elevate membrane AA phospholipid concentrations.
Prostaglandins, leukotrienes, and essential fatty acids  •  2002  |  View Paper
Supplementation with EPA significantly increased the proportion of EPA in the plasma CE and PL fractions, (both by 2.7-fold, day 4 and day 7) and in the RBC PL (by 1.9-fold, day 4 and day 7).
European Journal of Nutrition  •  2012  |  View Paper
Plasma phospholipid EPA levels increased significantly (P <0.0001) after supplementation with EPA , and DHA composition increased with DHA supplementation (P <0.0001).
Circulation  •  2000  |  View Paper
The proportion of EPA in PL showed a 15-fold increase after 7 d (P < 0.001), while DHA showed a smaller increase (P < 0.01).
The British journal of nutrition  •  1999  |  View Paper
EPA levels increased in serum phospholipid by 117% (from …/100 g fatty acids) and in platelet phospholipid by 176% (0.21 to 0.58 g/100 g fatty acids) via metabolic retroconversion; the … to EPA was 11.3 and 12.0%, based on the serum and platelet analyses, respectively.
The Journal of nutrition  •  1996  |  View Paper
EPA concentrations increased by 2.5-fold in the plasma lipid fractions and neutrophil phospholipids.
The American journal of clinical nutrition  •  1994  |  View Paper
First, EPA and DHA may compete for residency in membrane phospholipids and thereby differentially displace n-6 PUFAs, which are highly prevalent in the Western diet.
Nutrients  •  2020  |  View Paper
Our results also exhibited that treatment with 1 mM liposomes composed of SFP or SCP for 3 h tended to increase the EPA content in phospholipid fractions of both differentiated Caco-2 and M cells.
Food & function  •  2016  |  View Paper
This effect is apparently due to the incorporation of eicosapentaenoic acid in membrane phospholipids.
Cellular and Molecular Life Sciences CMLS  •  2002  |  View Paper
Small human trials confirmed that supplementation with eicosapentaenoic acid results in increased eicosapentaenoic acid in phospholipids and decreased generation of leukotrienes by neutrophils.
The American journal of clinical nutrition  •  2000  |  View Paper
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