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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Eicosapentaenoic Acid
drug:
Nitric Oxide
Research Papers that Mention the Interaction
“ No ' protective' effect of linoleic, linolenic or eicosapentaenoic acid was demonstrable.”
Relationships between nutrient intake and progression/regression of coronary atherosclerosis as assessed by serial quantitative angiography.“DHA and EPA also increased eNOS activity and induced nitric oxide production.”
“In SH‐SY5Y cells, EPA down‐regulated reactive oxygen species and nitric oxide.”
“These observations suggest that eicosapentaenoic acid potentiates the production of nitric oxide evoked by interleukin-1 beta in vascular smooth muscle.”
“ EPA also has antioxidant effects and increases synthesis of nitric oxide.”
“A plan to reduce emissions of nitrogen oxide was presented to the EPA in 2012, but was rejected by the Agency.”
“CONCLUSION EP , D HA have inhibitory effects on NO pr oduction, iNOS mRNA expression and DNA-binding activity of NFkappaB in monocyte.”
“In the endothelium, DHA and EPA improve function including increased nitric oxide bioavailability.”
Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and hypertension: a review of vasodilatory mechanisms of DHA and EPA.“Results: The results showed that EPA could increase the proliferation index and enhance the release of nitric oxide ( NO ) and cytokines in RAW264.7 cells.”
“Moreover, we show that vitamins A, D and omega-3 fatty acids (docosahexaenoic and eicosapentaenoic ) at concentrations where they individually had little effect, significantly reduced the secretion of the inflammatory mediator, nitric oxide , when they were combined.”
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