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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Eicosapentaenoic Acid
supplement:
Long Chain Fatty Acid
Research Papers that Mention the Interaction
“High dietary intake of long chain (n-3)-fatty acids can inhibit formation of many arachidonic acid-derived prostaglandins as well as stimulate formation of eicosapentaenoic acid-derived prostaglandins.”
Dietary (n-3)-fatty acids, prostaglandins, and prolonged gestation in humans.“Addition of 20:5omega3 eicosapentaenoic acid ) resulted in an increase of the relative levels of the long chain omega3 fatty acids at the expense of the omega6 fatty acids.”
Regulation of fatty acid biosynthesis as a possible mechanism for the mitoinhibitory effect of fumonisin B1 in primary rat hepatocytes.“Unsaturated LCFA downregulated transcription of measured genes, with a lesser effect by t10,c12-CLA and a stronger effect by DHA and EPA ; however, a basal activation of PPARγ was essential for the effect of t10,c12-CLA while the activation of PPARγ blocked the effect of DHA.”
Nutrigenomic Effect of Saturated and Unsaturated Long Chain Fatty Acids on Lipid-Related Genes in Goat Mammary Epithelial Cells: What Is the Role of PPARγ?
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