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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Eicosapentaenoic Acid and Ketoprofen

Research Papers that Mention the Interaction

Ketoprofen had a direct influence on the metabolism of EPA and resulting in conversion to its 15-LOX metabolite 15-HEPE.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V  •  2007  |  View Paper
If strongly bound ketoprofen:EPA complexes can form, then the permeation enhancement of EPA by ketoprofen could be attributed to such a complex.
NMR data revealed a dose-dependent change in chemical shift in the aromatic protons of ketoprofen on addition of fish oil and/or EPA.
The complexation of EPA with ketoprofen was probed in order to rationalise co-operative skin permeation enhancement behaviour observed previously.
International journal of pharmaceutics  •  2007  |  View Paper