“If strongly bound ketoprofen:EPA complexes can form, then the permeation enhancement of EPA by ketoprofen could be attributed to such a complex.”
“NMR data revealed a dose-dependent change in chemical shift in the aromatic protons of ketoprofen on addition of fish oil and/or EPA.”
“The complexation of EPA with ketoprofen was probed in order to rationalise co-operative skin permeation enhancement behaviour observed previously.”