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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Eicosapentaenoic Acid
supplement:
Fish Oils
Research Papers that Mention the Interaction
“ Fish oil supplementation raised eicosapentaenoic acid and docosahexaenoic acid content in plasma but not neutrophil phospholipids.”
Plasma and neutrophil fatty acid composition in advanced cancer patients and response to fish oil supplementation“We conclude that EPA appears to be primarily responsible for TG-lowering (and LDL-C raising) effects of fish oil.”
“Women supplemented with fish oil had increased levels of n−3 NEFA [ EPA , DHA, and docosapentaenoic acid (DPA)] prior to exercise.”
“… EPA … fish oil compared with those receiving control (absolute difference 0.5 [95% CI 0.3-0.7], 0.4 [0.1-0.6], and 0.…], and 0.3 [0.1-0.6] g/100 g total fatty acids for DHA; in plaque phospholipids, cholesteryl esters, and triacylglycerols, respectively).”
“ Fish oil resulted in a twofold increase in milk 22∶6n−3 levels, which peaked after 10 h and lasted for 24 h. The EPA content of milk was also increased by fish meals and fish oil supplements, but these had no effect on the level of arachidonic acid.”
“The level of eicosapentaenoic acid in plasma phospholipids did not change with placebo supplementation, but was significantly increased with fish oil supplementation in both young male and elderly subjects (median increase 200%).”
“Enhancement of 20: 5 omega 3 eicosapentaenoic acid ) and 22:6 omega 3 (docosahexaenoic acid) and suppression of 20:4 omega 6 (arachidonate) after supplementation with fish oil were accompanied by important decreases in proteinuria and improved glomerular filtration rate.”
“… fish oil, … eicosapentaenoic acid/arachidonic acid ratio in plasma increased 9.8-fold, from 0.04 +/- 0.02 (mean +/- SEM) to 0.39 +/- 0.11 (p = 0.02), … without CF (n = 8) who received fish oil (p = 0.02, patients with CF vs subjects without CF at 6 weeks).”
“Plasma EPA and DHA levels rose after fish oil intake and fell after corn oil intake (all p less than 0.001).”
“Dietary supplementation with fish oil resulted in a significant increase in EPA in neutrophil phospholipids that was greater in group L (mean 2.0 +/- 0.4%) than group H (mean 1.5 +/- 0.3%; P less than 0.005).”
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