supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Eicosapentaenoic Acid
supplement:
Fatty Acids, Omega-6
Research Papers that Mention the Interaction
“Our study indicates that the ingestion of n-6 fatty acids within the diet is an important determinant of EPA incorporation into neutrophil membranes.”
Linoleate inhibits EPA incorporation from dietary fish-oil supplements in human subjects.“Docosahexaenoic acid- and eicosapentaenoic acid-derived eicosanoids antagonize the pro-inflammatory effects of n-6 fatty acids.”
“Feeding fish meal and fish oil containing eicosapentaenoic acid and docosahexaenoic acid reduced the proportion of n-6 fatty acids and increased that of n-3 fatty acids in milk in a dose-responsive manner.”
Uterine, ovarian, and production responses of lactating dairy cows to increasing dietary concentrations of menhaden fish meal.“…)n-6 fatty acids … EPA to 22:5 whereas n-3 fatty acids inhibited the delta 5 desaturation of DHLA to AA and the elongation of AA … (33%) reduction in the bradykinin-induced release of PGE1 and PGE2, whereas n-6 fatty acids stimulated PGE3 release 2.3-fold.”
“ EPA supplementation decreased the level of some n-6 fatty acids such as arachidonic acid.”
Effects of EPA supplementation on plasma fatty acids composition in hypertriglyceridemic subjects with FABP2 and PPARα genotypes
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback