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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Eicosapentaenoic Acid
supplement:
Eicosatrienoic Acid
Research Papers that Mention the Interaction
“The desaturation products AA, EPA , and DHA inhibit delta 6 desaturation of LA and delta 5 desaturation of DGLA (dihomo-gamma-linolenic acid).”
The metabolism and availability of essential fatty acids in animal and human tissues.“High doses of EPA given to Westerners also lower levels of dihomogammalinolenic acid (DGLA), a substance with a wide range of desirable cardiovascular and antiinflammatory actions.”
“We suggest that eicosapentaenoic acid might be a better antithrombotic agent than dihomogammalinolenic acid.”
“This result suggested that EPA but not DHA in fish oil exerts an inhibitory effect on the conversion of DGLA to AA.”
The influence of dietary manipulation with n−3 and n−6 fatty acids on liver and plasma phospholipid fatty acids in rats“Only small effects on the uptake of 10 microM eicosapentaenoic acid occurred when palmitic, stearic or oleic acids were added to the medium in concentrations up to 75 microM. In contrast, eicosapentaenoic acid uptake was reduced considerably by the presence of linoleic, n-6 eicosatrienoic , arachidonic or docosahexaenoic acids.”
“Baseline eicosapentaenoic acid levels were modestly correlated with suicidal ideation at follow-up and dihomo-γ-linolenic acid and arachidonic acid were modestly correlated with motor impulsivity at follow-up in cases.”
Lipids and polyunsaturated fatty acid levels in deliberate self-harm: a 10-year follow-up study
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