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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Eicosapentaenoic Acid and Curcumin

Research Papers that Mention the Interaction

In response to TNF-α (25 ng ml−1)-induced protein degradation, EPA had a small, but not significant effect on protein degradation; however, when curcumin and GTE were combined with EPA , the effect was enhanced.
The combination of EPA with curcumin produced a significant increase in protein synthesis to both agents.
These results suggest that either curcumin or GTE or the combination could enhance the anti-catabolic effect of EPA on lean body mass.
This study investigates whether curcumin or green tea extract (GTE) enhances the ability of low doses of eicosapentaenoic acid (EPA) to reduce loss of muscle protein in an in vitro model.
In Vitro Cellular & Developmental Biology - Animal  •  2016  |  View Paper
All the combinations of CUR and DHA or EPA with lower concentrations of CUR 5 microM and 25 microM of DHA or EPA were found to have synergistic effects in suppressing LPS-stimulated NO and endogenous NO levels.
Biochemical pharmacology  •  2010  |  View Paper
Feeding of the curcumin diet caused a significant increase in the concentrations of tetrahydrocurcumin, arachidonic acid and eicosapentaenoic acid and a significant decrease in thiobarbituric acid-reactive substance concentration in serum.
Carcinogenesis  •  1999  |  View Paper