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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Eicosapentaenoic Acid
drug:
Cardiotonic Agents
Research Papers that Mention the Interaction
“BACKGROUND The lipid-modulatory effects of high intakes of the fish-oil fatty acids eicosapentaenoic acid EPA ) and docosahexaenoic acid (DHA) are well established and likely to contribute to cardioprotective benefits.”
Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN Study.“Treatment with the omega-3 polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) exerts cardioprotective effects , and suppresses Ca2+-induced opening of the mitochondrial permeability transition pore (MPTP).”
Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.
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