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Last Updated: 2 years ago

Possible Interaction: Eicosapentaenoic Acid and Antioxidants

supplement:

Antioxidants

Research Papers that Mention the Interaction

EPA and nutritional antioxidants may show complementary activities in a wide range of preventive and therapeutic applications.
Medical hypotheses  •  1987  |  View Paper
Additionally, EPA treatment increased Nrf2 nuclear translocation and antioxidant response element activity, leading to the upregulation of HO-1 expression.
Journal of cardiovascular pharmacology  •  2015  |  View Paper
Both inhibition of the COX pathway by indomethacin as well as inhibition of direct lipid peroxidation by antioxidants such as vitamin E and C diminished the anti-proliferative effects of AA as well as EPA.
Carcinogenesis  •  2003  |  View Paper
We observed that different antioxidants counteracted the necrotic effect of EPA on Raji cells to a different extent, and that vitamin E counteracted EPA-induced accumulation of superoxide anion in this cell line.
Lipids  •  2001  |  View Paper
The action of EPA could be reversed with the anti-oxidant vitamin E acetate or with oleic acid.
British Journal of Cancer  •  1994  |  View Paper
On the other hand, the anti-oxidant , vitamin E, and the superoxide anion quencher, superoxide dismutase (SOD), could completely inhibit the cytotoxic action of GLA, EPA and DHA indicating a role for free radicals and, in particular, the superoxide anion in this process.
Cancer letters  •  1994  |  View Paper
The addition of antioxidant condiments, and herbs in particular, may retard PUFA peroxidation and preserve EPA and DHA during pan-frying.
Biomolecules  •  2019  |  View Paper
Since both EPA and its derivatives have been reported to enhance the antioxidant mechanism, the present study aimed at studying whether EPA could offer protection against TCDD-induced oxidative stress and nephrotoxicity in Wistar rats.
Cell Stress and Chaperones  •  2013  |  View Paper
osapentaenoic acid plus B3 had synergistic effects leading to decreased nitric oxide levels; the modulation of phosphoprotein levels, such as P-nuclear factor-[kappa] B p65 … protein kinase/Jun-amino-terminal kinase; the down-regulation of proinflammatory genes, such as interleukins, chemokines, transcription factors; and up-regulation of ant ioxidant genes.
Nutrition  •  2012  |  View Paper
Lipoic-EPA was the best absorbed of the three compounds and its combination of anti-oxidant together with EPA lowered the calcium content of both the aortas and the kidneys.
Prostaglandins, leukotrienes, and essential fatty acids  •  1998  |  View Paper
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