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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Eicosapentaenoic Acid
Research Papers that Mention the Interaction
“ EPA may, furthermore, enhance the action of antidepressants , like many SSRIs that are p-gp substrates, which are actively transported out of the intracerebral space at the level of the blood-brain barrier.”
Ethyl-eicosapentaenoate and dexamethasone resistance in therapy-refractory depression.“OBJECTIVE Studies of depressed psychiatric patients have suggested that antidepressant efficacy can be increased by adding eicosapentaenoic acid (EPA), one of the omega-3 fatty acids found in fish oils.”
“Future precision medicine trials should establish whether possible interactions between EPA and antidepressants could provide targets to improve antidepressant response and its prediction.”
“When adjusted for potential confounders, such as sociodemographic characteristics and health indicators, plasma EPA was inversely associated with the severity of DS (beta = -0.170, P = 0.040) in subjects taking antidepressants.”
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