Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Edetic Acid and Urea

supplement:

Edetic Acid

drug:

Urea

Research Papers that Mention the Interaction

The lectin did not lose its activity in the presence of urea but the activity lost significantly when treated with EDTA.
International journal of biological macromolecules  •  2019  |  View Paper
The AHL activity was gradually lost in the presence of urea and completely lost when being treated with ethylenediaminetetraacetic acid (EDTA).
International immunopharmacology  •  2019  |  View Paper
The activities remained unaffected after heat and urea treatment of EPS, but were significantly reduced by the ethylenediaminetetraacetic acid (EDTA) treatment.
Water environment research : a research publication of the Water Environment Federation  •  2009  |  View Paper
Formation of the species of lower molecular mass during urea activation could be blocked by the addition of EDTA.
Acta biochimica Polonica  •  1990  |  View Paper
The complex disassociates in the presence of EDTA and urea.
The Biochemical journal  •  1983  |  View Paper
Urea inhibited the enzyme activity at concentrations above 1.5 M, while EDTA and EGTA were strong inhibitors at very low concentrations.
Acta odontologica Scandinavica  •  1977  |  View Paper
Heat and urea potentiate the inhibition seen with EDTA.
Archives of biochemistry and biophysics  •  1969  |  View Paper
Although EDTA does not inhibit the deaminase at 10°, the inhibition by urea , N-ethylmaleimide, and 5,5'-dithiobis(2-nitrobenzoic acid) is dramatically enhanced in its presence.
The Journal of biological chemistry  •  1968  |  View Paper
Metal ions Mn+2 markedly improved the enzyme activity, while exposure to urea and ethylenediaminetetraacetic acid drastically inhibited the biocatalytic performance.
Biochimica et biophysica acta. Proteins and proteomics  •  2020  |  View Paper
A loss of enzymatic activity is observed upon removal of zinc from the wild-type MetE by incubation in urea and EDTA ; activity can subsequently be restored by zinc reconstitution, suggesting that zinc is required for catalysis.
Biochemistry  •  1996  |  View Paper