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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Edetic Acid
drug:
Ubenimex
Research Papers that Mention the Interaction
“The enzyme activity was strongly inhibited by bestatin and was negatively affected by ethylenediaminetetraacetic acid ( EDTA).”
Purification and Characterization of Porcine Skeletal Muscle Aminopeptidase T, a Novel Metallopeptidase Homologous to Leukotriene A4 Hydrolase“No significant endoglucanase activity was measured, either for TmPep1050 or CelM. Addition of cobalt ions enhanced the activity of both enzymes significantly, while both the chelating agent EDTA and bestatin , a specific inhibitor of metalloaminopeptidases, proved inhibitory.”
Functional Characterization of Two M42 Aminopeptidases Erroneously Annotated as Cellulases“ Bestatin behaved as a competitive inhibitor of LAP yspII (Ki = 0.14 µm), while chelating agents such as chloroquine, EDTA and 1,10‐phenanthroline also reduced enzyme activity.”
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