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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Edetic Acid
drug:
Sodium Chloride
Research Papers that Mention the Interaction
“The enzyme was more sensitive to 1,10 phenanthroline than EDTA and was 80% inhibited in presence of NaCl.”
Biochemical characterization of dipeptidylcarboxypeptidase of Leishmania donovani.“This was prevented by adding NaCl to the EDTA solution.”
“It was affected by Ca2+, inhibited by EDTA , and activated eight-fold by NaCl.”
Purification and characterization of two alpha-amylases from Toxoplasma gondii.“The enzyme activity was not affected by the addition of 4% (w/v) NaCl and different metal ions (Co+2, Fe+2, Mg+2, Ni+2, and Zn+2) at 25 mmol l-1 but was strongly inhibited by EDTA.”
“ NaCl increases the dissociation rate far more in assays performed in EDTA , while binding in the presence of MgSO4 is more sensitive to the stabilized GTP analog 5'-guanylylimidodiphosphate.”
“The simultaneous presence of NaCl with EDTA exacerbates such an inactivation, although NaCl by itself does not.”
“1) The effectiveness of salicylate or EDTA was enhanced by sodium chloride , whereas the activity of POE was not. (”
“ Sodium chloride was required for activation of the enzyme, and it was inhibited by EDTA , bradykinin potentiating factor-nonapeptide, and angiotensin 2, but not by histidylleucine.”
“Both deferoxamine (DFO) and ethylenediaminetetraacetic acid (EDTA) reduced lipid oxidation in emulsions with NaCl , with EDTA being more effective.”
Effects of salts on oxidative stability of lipids in Tween-20 stabilized oil-in-water emulsions.“The enzyme activity was increased 40% by 0.15 M NaCl , inhibited 94% by 2.0 mM Zn2+, inhibited 91% by sodium p-hydroxymercuribenzoate and inhibited 45% by 0.7 mM o-phenanthroline and 30 microM EDTA.”
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