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Last Updated: 3 years ago

Possible Interaction: Edetic Acid and Sincalide

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supplement:

Edetic Acid

drug:

Sincalide

Research Papers that Mention the Interaction

“ Ethylenediaminetetraacetic acid , but not aprotinin, inhibited the cleavage of CCK-33 to produce CCK-8, and the degradation of CCK-8 in normal plasma in vitro.”

Cholecystokinin cleavage to cholecystokinin-octapeptide in vivo and in vitro: accelerated cleavage in acute pancreatitis.

Gastroenterology • 1988 | View Paper

“The cleavage of CCK-8 and gastrin analogues was inhibited by ACE inhibitors (Captopril and EDTA ), but not by other enzyme inhibitors (phosphoramidon, thiorphan, bestatin etc.).”

Novel activity of angiotensin-converting enzyme. Hydrolysis of cholecystokinin and gastrin analogues with release of the amidated C-terminal dipeptide.

The Biochemical journal • 1989 | View Paper

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