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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Edetic Acid and Polypeptides

supplement:

Edetic Acid

supplement:

Polypeptides

Research Papers that Mention the Interaction

The processing from the 65- to the 45-kDa polypeptide in the test tube was inhibited by ethylenediaminetetraacetic acid but not by N-ethylmaleimide and aminophenylmethylsulfonyl fluoride.
Biochimica et biophysica acta  •  1995  |  View Paper
Binding is metal-dependent and treatment of the polypeptide with EDTA abolishes binding.
Journal of molecular biology  •  1992  |  View Paper
Pulse-chase experiments indicated that the 190-kd polypeptide was secreted into the culture medium in 2 h and processed to the 120-kd collagen component within 4 h. This process was inhibited by EDTA.
The Journal of investigative dermatology  •  1991  |  View Paper
Protease inhibitors, in particular EDTA , a metalloprotease inhibitor, dramatically increases the predominance of the Mr = 78,000-85,000 polypeptide while attenuating the labeling of the lower molecular weight bands.
The Journal of biological chemistry  •  1984  |  View Paper
Three polypeptides of the puromycin-derived subunit, SP0, LP1, LP3, are stripped by the sole removal of Mg2+ when EDTA is used.
European journal of biochemistry  •  1981  |  View Paper
Furthermore, EDTA robustly suppressed surface polypeptide synthesis, suggesting a decline in the possible bacterial ligands responsible for S. agalactiae adhesive properties.
Molecular medicine reports  •  2009  |  View Paper
Breakdown of the 31 kDa polypeptide in vitro was Mg2+-dependent and inhibited by EDTA and transition metal ions.
Photosynthesis Research  •  2004  |  View Paper
The polypeptides truncated by the EDTA treatment reduced Ca binding capacities compared to their native subunits, indicating a Ca-binding site within the conserved duplicated region.
Biochemistry  •  1996  |  View Paper